منابع مشابه
Commentary: Advent of sibling designs.
Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder. Pediatrics 2009;124: e1054–63. 22 Biederman J, Monuteaux MC, Faraone SV, Mick E. Parsing the associations between prenatal exposure to nicotine and offspring psychopathology in a nonreferred sample. J Adolesc Health 2009;45:142–48. 23 Thapar A, Rice F, Hay D, Boivin J et al. Response to: testing the associa...
متن کاملSibling comparison designs: bias from non-shared confounders and measurement error.
Twins, full siblings, and half-siblings are increasingly used as comparison groups in matched cohort and matched case-control studies. The "within-pair" estimates acquired through these comparisons are free from confounding from all factors that are shared by the siblings. This has made sibling comparisons popular in studying associations thought likely to suffer confounding from socioeconomic ...
متن کاملA new score statistic to test for association given linkage in affected sibling pair-control designs
To detect association of the DR1 allele with rheumatoid arthritis (RA) given linkage in the affected sibling pairs of the replicates of Problem 3 of Genetic Analysis Workshop 15 (GAW15), we propose a new score statistic that takes into account the linkage information. We knew the answers. Linkage studies are often followed by case-control association studies of candidate genes located under the...
متن کاملUsing Sibling Designs to Understand Neurodevelopmental Disorders: From Genes and Environments to Prevention Programming
Neurodevelopmental disorders represent a broad class of childhood neurological conditions that have a significant bearing on the wellbeing of children, families, and communities. In this review, we draw on evidence from two common and widely studied neurodevelopmental disorders-autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD)-to demonstrate the utility of genet...
متن کاملA tutorial on Quasi-experimental designs
A main step in answering a scientific hypothesis in an epidemiological study is deciding which type of study is suitable to be undertaken, considering methodology, practical considerations and budget and time limitations
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ژورنال
عنوان ژورنال: Epidemiology
سال: 2013
ISSN: 1044-3983
DOI: 10.1097/ede.0b013e31828c7381